The second relates to understanding mechanisms that lead to increased cerebral vascular risk during preeclampsia. Using an experimental model of the autoimmune disorder systemic lupus erythematosus (SLE), Professor Ryan’s laboratory has contributed significantly to the understanding of both renal and vascular mechanisms during SLE, and how they are influenced by inflammatory cells and mediators. Evidence suggests that human hypertension is associated with immune dysfunction including the production of autoantibodies commonly associated with autoimmune disease. The first relates to understanding how immune system activation mechanistically promotes the pathogenesis of hypertension. Professor Ryan’s laboratory has made research contributions in two major areas. Subject area: Nephrology and Circulation, Vascular Biologyīiography: Professor Michael Ryan is the Associate Chief of Staff for Research at the William Jennings Bryan Dorn Veterans Affairs Hospital, and a Professor of Pharmacology, Physiology & Neuroscience at the University of South Carolina School of Medicine in Columbia, SC. Associate Editors from this journal are participating in our ECR Editorial Board Mentorship Scheme >Īffiliation: William Jennings Bryan Dorn VA, University of South Carolina School of Medicine, Columbia, USA
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